While not all hyperpigmentation is serious, if it occurs on the legs or is a golden-brown-yellow tone, it can indicate that you may have a condition compromising blood flow. Of course, a doctor may suggest dieting or lifestyle change to help manage blood circulation in your legs. People experience many kinds of skin changes over time. The brown marks (Haemosiderin) occur because of the venous blood refluxing the wrong way down the veins. An Iron shortage may cause the body to use the reserve iron when the stain fades away. Hemosiderin staining looks like a patch of skin that is a darker color than the surrounding skin. In some cases, a blood test may also be ordered to check for levels of ferritin, which is a protein that stores iron in the body. That way, you can compare the pictures and measurements in regards to the earlier shots. Microdermabrasion is a type of exfoliation that removes the top layer of skin, which can help to reduce the appearance of hemosiderin staining. Advanced age (due to the diseases progressive nature and other factors), Certain medications (discuss with your physician), Keloid scarring from prior procedures or injury, It means the treatments have worked and those veins are shut down, and, This type of discoloration/staining is not permanent. Dermato Cosmetologys cream focuses on delivering vitamin K to the targeted area. One of the major causes of the staining is leaking vessels, leading to excess iron deposits. This can also lead to chronic pain as well as stiffness in the leg joint. Chronic inflammation can also lead to hemosiderin staining. Elevate your legs when you sit or lie down. Because some of the veins are still open, and diseased, the body cannot properly close treated veins and absorb them. Hemosiderin a protein compound that stores iron in your tissues can accumulate under your skin. Here are the 15 best vitamin brands to help. Perls' Prussian blue stain was used to detect haemosiderin-laden macrophages. Hemosiderin staining is more common in people with certain risk factors. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. These creams generally help to make the iron in hemosiderin more accessible to the body, and expediting its consumption. Hemoglobin contains iron, which causes the rusty color of the stains., Hemosiderin staining is usually a symptom of a condition in the blood vessels in your legs called chronic venous insufficiency. This condition takes place around the superficial veins closest to the skin surface. As a result, you may notice yellow, brown, or black staining or a bruiselike appearance. A valve failure might be due to a condition known as Chronic venous insufficiency(CVI). Health news fact-checking is important because of the way the internet works. It may be harder to spot if you have a dark skin tone. The skin changes can be an indication of poor blood circulation that can trigger chronic pain and other serious medical complications like leg ulcers and skin infections. Even if the affected area on the surface is targeted, the underlying veins might still leak. Usually, this discoloration varies in size, shape, and location on the leg. This can happen for a variety of reasons, including: -Certain medical conditions that cause the body to absorb too much iron. This leads to the overabundance of blood cell breakdown and iron accumulation. If you recognize the underlying cause early and start managing the condition, the stains may fade somewhat over time. Patients often describe this staining as a shadow of where the treated veins once were. 2005 - 2023 WebMD LLC. Hemosiderin is conspicuous in venous stasis of the lower legs. In most cases, hemosiderin staining is a benign finding that does not require treatment. Hemosiderin staining is more than an eye sore. When damage occurs, the surrounding tissue is flooded with blood and a bruise then forms. Permanent Bruises (Hemosiderin Staining): Causes, Risks, and Treatment, Topical Creams for Hemosiderin Staining Top Products, American Society for Experimental Neurotherapeutics. Using arnica montana (wolfs bane) flower extract, vitamin K, and African ginger, this cream accelerates the bodys natural healing process to improve the skins appearance. Fontana-Masson or Schmorl's ferric-ferricyanide reduction stain can be used to identify melanin granules. Get guidance about dietary and lifestyle changes and desirable treatment. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. It tends to be golden brown, more refractile, and more clumped than melanin (1.79), but the distinction can be difficult at times, requiring special melanin stains or iron stains. Its more important than ever to ensure that all news articles include original commentary from at least one qualified source. Other risk factors of developing this include:. Users have said that they notice results after as few as three applications. JAMA Dermatol. Seeing your skin change tones can be alarming. The side-effect is rare and most notably affects people with severe iron deficiency anemia. Read our. Hemosiderin Staining is the appearance of brownish patches above the ankles that usually occur when red blood cells break down and begin to leak iron. in the realm of surgery, hemosiderin staining is a sequela of hematoma/bruising. The first line of defense is a good offense. The veins contain one-way valves to stop the blood falling back towards the toes. Hemosiderin staining usually happens on the lower leg . In a normal venous system, blood travels upward towards the heart, via one-way valves. . Chronic Vein Disease What causes them, and what you can do about them. Hemosiderin can be identified histologically with 'Perls' Prussian-blue' stain. Staining is unlikely to vanish naturally, and the typical treatments, which target the stain itself, will not be effective in the long-term. In this blog, we are going to talk about an irksome complaint from those suffering fromvaricose vein disease: hemosiderin staining or skin discoloration. Our team consists of doctors and experts who ensure the information we provide is medically accurate. Bruises form when blood vessels are injured, resulting in blood leaking to nearby tissues. Again, even creams for hemosiderin staining may make the staining worse. Pigmentation disorders are often more troublesome in skin of colour. Skin staining following intravenous iron infusion, Hemosiderin hyperpigmentation: Successful treatment with Q-switched 755-nm laser therapy. The haemoglobin from red blood cells is released into the skin tissue and degrades into hemosiderin. This can cause a number of symptoms, including fatigue, joint pain, and shortness of breath. Weve put together some resources to help in your everyday work. A dysfunctional blood valve causes chronic venous insufficiency(CVI). The staining alone isnt life-threatening, but it can be an indication of a more serious condition. We use cookies to ensure that we give you the best experience on our website. Can Standing Too Long Cause Varicose Veins? Ankle discoloration can be patchy or widespread. But, in rare cases, younger people are affected independently. Does Paula Jai Parker Have Siblings? The official term for skin discoloration is hemosiderin staining and it is more common than you think. As such, typical treatment methods wont offer a permanent solution. Hemosiderin staining occurs when red blood cells are broken down, causing hemoglobin to be stored as hemosiderin. What Causes Hemosiderin Staining? You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. Internally, hemosiderin staining of the liver can be a sign of hemochromatosis, or an iron surplus in the body. This is caused by: Incompetent venous valves Venous outflow obstruction Dysfunction of the calf muscle pump [2]. While staining caused by CVI is usually reddish-brown in color, staining which occurs following treatments of CVI is of a blueish-brown hue and is often along the pathway of the treated veins. . Lets look at some of the conditions associated with hemosiderin staining. The risk of developing chronic venous insufficiency increases: Read more about the most common risk factors of chronic venous insufficiency here. The most notable condition that causes hemosiderin staining is chronic venous insufficiency (CVI). The trapped iron is then stored as hemosiderin in tissues beneath your skin, causing visible hemosiderin staining. Our website services, content, and products are for informational purposes only. Hemoglobin contains iron, which causes the rusty color of the stains. They will help investigate the cause and enact a proper treatment. CVI occurs when these valves no longer function, causing the blood to pool in the legs. A bruise, or contusion, occurs when an area of skin has suffered trauma. Most of the time, staining after these procedures usually clear up on its own after a few months to a year. Hemosiderin staining is a permanent or semi-permanent, bruise-like mark that can vary dramatically in size, shape, and location on the body. Doru Paul, MD, is triple board-certified in medical oncology, hematology, and internal medicine. The test most used for CVI is known as a Duplex ultrasound. What you see are the components of the red blood cells, including iron, among other elements. Treatments for hemosiderin discoloration may first focus on the condition causing it. You should not take hemosiderin staining lightly because of its adverse effects. What causes hemosiderin staining? It is advisable not to use bleaching creams because the iron is too deep. [3] Hemosiderin is also generated from the abnormal metabolic pathway of ferritin. When an excessive amount of haemoglobin is stored as hemosiderin inside the cells, Hemosiderin staining occurs. Eur Rev Med Pharmacol Sci. But some medical conditions can overwhelm this process and lead to a blemish. 2021 Dec;25(24):7777-7786. doi:10.26355/eurrev_202112_27624, Crowley CM, McMahon G, Desmond J, Imcha M. Skin staining following intravenous iron infusion. The image will help you measure the stain size as the topical treatment take effect. The staining itself often comes without pain. The process is relatively painless, and you can do it within one or two doctors visits. This approach makes the cream a versatile option that may help to not only treat bruising, but also under-eye circles, varicose veins, and spider veins. But there are some medical conditions that can overwhelm this process, resulting in a stain. When red blood cells break down, the hemoglobin releases iron. Hemosiderin staining is a condition where iron deposits build up in the skin, causing it to take on a brown or blue-black tint. If you notice discolored marks on your body or experience other skin changes such as itching, flaking, bleeding, swelling, redness or warmth, schedule a visit with your doctor to discuss possible diagnoses and treatments. Medical providers will examine the area and take a medical history to diagnose hemosiderin straining. Generally, stains that last more than 12 months cause permanent marks as the skin has essentially been tattooed. It is commonly seen in patients who have undergone surgical . A Increase font size. Does hemosiderin staining go away? The melanocytes of dark-skinned people produce more melanin than those of people with light skin. So if the body can ingest the iron, then the staining will go away. Hemosiderin staining is not only a cosmetic issue. When red blood cells break down, the hemoglobin they carry releases iron. Varicose eczema is usually caused by increased pressure in the leg veins. Noticeably, venous stasis will occur on your ankle. In order to hasten the absorption of the iron present in hemosiderin, some sources suggest altering diets to reduce the total amount of iron in the body. Wild Thera recommends frequent application, as often as several times per hour, for optimal result. In the process, it stops extra blood from leaking to your lower legs and ankles. Those affected by chronic venous insufficiency (CVI), also known as varicose vein disease, often experience staining. Thus, many methods of iron storage have developed. I dont know about you, but I dont want to wait 3-6 months for my legs to look better. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Treatment for Chronic Venous Insufficiency, Swelling, especially after long periods of sitting or standing still, Family history of chronic venous insufficiency, High blood pressure in the leg veins due to sitting or standing for long periods. The trapped iron is then stored as hemosiderin in tissues beneath your skin, causing visible hemosiderin staining. Several options exist to speed up the healing process. Hemosiderin staining is a medical condition in which one presents yellow or brown patches on the skin. In cases where damage is more severe and veins continue to leak long after the initial injury occurs, treatment can be more difficult. This creates pools of blood that result in hemosiderin staining. People with these conditions may be more likely to have hemosiderin staining. If it occurs as a result of a blood clotting disorder, it is frequently referred to as thrombicytopenia pureniapura. Terms of Use This bruise fading balm goes the natural route by incorporating organic herbs and essential oils into its non-GMO mix. Here Is The Truth. If you do notice leg discoloration, or hemosiderin staining, take action. There is no cure for hemosiderin staining, but treatment focuses on managing symptoms and preventing complications. Hemosiderin is an abnormal microscopic iron-containing compound found in the human body. You can learn more about how we ensure our content is accurate and current by reading our. Medications, wound care, or vein surgery may be needed., Hemosiderin staining is something to be checked out since its related to the blood flow in your body. Contact details020 3819 6022hello@acceleratecic.comFind out more on the Accelerate website. Move your leg often. To be on the safe side, you need to consult experts. Hemosiderin staining is a common problem that can occur when iron deposits build up in the body. Some of the most common symptoms of vein disease include leg aching, pain, heaviness, restlessness. While creams specifically designed to deal with hemosiderin staining can potentially alleviate the issue, skin bleaches are not recommended for this purpose because the iron pigment is too deep in the skin to be accessed by the bleaching agents. What causes hemosiderin staining? Hemosiderin Staining. At Healthroid, all articles, references and academic papers are from respected sources and credible journals or institutions. If the veins are still leaking, then the hemosiderin stain might not disappear anytime soon. Consuming less iron makes the body rely on its stored reserves. Trauma, such as breaking a bone, is among the potential causes of hemosiderin staining. The melanocytes ( pigment cells) are located at the base of the epidermis and produce the protein melanin. For that reason, you must cure that problem. If you suffer from chronic venous insufficiency you are not alone; in fact, it is estimated that one in ten people in the United States suffer from varicose vein disease. Staining is represented by a brownish discoloration either in the vein or around it.. Lets dig deeper into and learn the composition of hemosiderin. Excess Iron in the body is referred to as hemochromatosis. But what is more, there are other underlying problems caused by the staining. Some common conditions associated with hemosiderin staining include: If your hemosiderin staining occurred as a side effect of skin injury or treatments, it will likely clear up on its own. The blood pools under the skin and leave a residue of hemoglobin that settles in the tissue there. The makers of Heladerm recommend its application to the affected area two to three times per day for best results. In severe cases, you may get cirrhosis of the liver, among other conditions. Treatment for varicose or spider veins, known as sclerotherapy, can also induce pigment changes caused by a buildup of iron beneath the skin. The doctor may put you in meds, wounds treatment, or even surgery in such a case. This happens because of hemoglobin, a protein molecule that contains iron. But before you start dieting immediately, its good to note a few things. [button btn_url=https://www.amazon.com/gp/product/B01GBVAO5C/ref=as_li_tl?ie=UTF8&tag=zwivel-20&camp=1789&creative=9325&linkCode=as2&creativeASIN=B01GBVAO5C&linkId=2891f5addf5f98ff4ff7867d41d0357a btn_color=orange btn_size=medium btn_style=default btn_outlined=no link_target=blank link_rel= icon_left= icon_right=]Check Price[/button]. Time may help the color fade as long as the initial cause is also eliminat. Your white blood cells, or immune system cells, can clear up some of the excess. Hemosiderin is essentially a blood stain, on human tissue. Disclaimer: USA Vein Clinics makes every effort to treat your vein problem. Hemosiderin (a breakdown product of hemoglobin) causes staining of tissue after lipo or other surgical procedures. Over time, these valves can weaken, and blood doesnt flow upward the way it should. USA Vein Clinics will not guarantee any specific results and results may vary by individual patient. When you deal with chronic venous insufficiency, your skin will look better. Hamilton HK, et al. Hemosiderin staining occurs in patients who have undergone surgical intervention or in those who have . I was told it is hemosiderin. This can be due to blood loss, poor absorption of iron, or increased need for iron. The process starts with hemoglobin (a protein that transports oxygen throughout the body). The iron deposits can cause problems with organ function, and can also lead to anemia. Its caused by blood leaking out of the tiny vessels called capillaries. Hemosiderin staining might signify critical conditions such as heart disease. People with . It is often seen in people with chronic illnesses such as liver disease, heart failure, and cancer. In some cases, discoloration may last longer than 3 weeks. Bruises are caused when an impact damages blood vessels and allows blood to seep into surrounding tissues. Osteopathic Family Physician. Checking the websites source, or if the article is from a peer-reviewed journal, can help ensure that you are getting accurate information. Hemosiderin staining occurs when red blood cells spill out of the smallest blood vessels (capillaries). All rights reserved. If you are patient enough, you can wait it out on some of the hemosiderin stainings disappearing independently. Lets see what it is all about. The leaking veins feed the stain. Taking steps to improve your circulation will help your overall health. The pigment may lighten over time, but not in all cases. We are a coalition of healthcare organisations that have come together to make sure that anyone with a lower leg or foot problem understands their condition and receives the urgent care, attention and support they need. The technical term for this is hemosiderin staining. All in all, hemosiderin is treatable. All Healthroid articles adhere to the following standards: This article is written by a medical writer and reviewed by medical professionals. Over time, certain hemosiderin stains will fade naturally as the body slowly uses up the stored iron. Melanin is carried by keratinocytes to the skin surface. Hemosiderin staining mostly appears on the lower leg, between the knee and ankle. Are There Tests to Diagnose the Cause of Hemosiderin? The injury causes blood vessels to burst, trapping blood below the skin's, Ritual is a subscription-based vitamin company that offers protein powders and multivitamins for people of all ages. The underlying cause of DAD was identifiable in 17 (81%) patients, and . As a result, you may develop localized skin conditions including: There are treatments available to lighten or reduce staining due to trauma or skin procedures. . Notably, the stain might lighten over time, but this depends on the source of the staining. In some instances, the injection may leave you with brown skin discoloration because of the surplus iron in the hemosiderin. That my friend, is most likely hemosiderin staining. This is because inflammatory cells release iron as they break down tissue. The ulcers take time to heal. Hemosiderin staining is one of the signals that show something is not right with your veins. It happens most often in people over 50 years old or in people who have previously had blood clots in their legs. Pictures and symptoms of the red, scaly rash. Laser therapy uses light energy to break down the iron deposits in the skin. Patchy ankle discoloration sometimes looks like freckles or "sun-spots." Wounds UK compression hosiery(PDF Download Open access registration required to download). Venous hypertension / insufficiency happens when high pressure in the veins in the legs causes substances from the blood to leak into the tissues. Sign up and consent for campaign updates, straight to your inbox. You may need to make lifestyle changes to help fix the condition. Keep in mind that the body can and does produce materials that can show up on a H&E stains as pigment. Hemosiderin contains iron thats not easily consumable by the body. Phagocytes are a grouping of white blood cells that ingest harmful substances in the body. This ensures all diseased veins are treated appropriately. Chronic venous insufficiency. This article reviews the, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. The other form of treatment is cosmetic sclerotherapy. If a laser or chemical peel is used, it may take two to three or . Hemosiderin hyperpigmentation: Successful treatment with Q-switched 755-nm laser therapy. The number one cause of staining followingsclerotherapy vein treatmentis the need for some touch up treatments. For one, there are no proven results on this method. Answer: Speeding Up Hemosiderin Staining Rhinoplasty Post-Op At one month post-op, you are still healing. This test screens for clinically significant arterial impairment. It typically occurs around superficial veins, close to the surface of the skin, says Dr. Aaron Shiloh of Shiloh Vein and Aesthetics, located just outside of Philadelphia. We're based in East London but can accept national referrals from your GP / specialist to our world-class centre where we pioneer and trial experimental new treatments for chronic wounds, lymphoedema and mobility challenges. However, if a person takes too much iron and has a condition that can cause blood pooling, they may be at risk of hemosiderin staining. Causes of Brown Skin Marks. The patient's individual skin type may also influence the success of laser treatment. Hemosiderin staining can also occur after vein treatments like sclerotherapy or surface laser treatments. ( pigment cells ) are located at the base of the excess more important than ever to that., restlessness, then the hemosiderin stain might not disappear anytime soon as well as stiffness in the leg.... Travels upward towards the toes the test most used for CVI is known as chronic venous (. Trauma, such as heart disease few months to a year may make the staining worse phagocytes are a of... Even if the article is written by a medical history to diagnose hemosiderin.. To use bleaching creams because the iron in hemosiderin staining occurs when red cells... Hemoglobin ) causes staining of tissue after lipo or other surgical procedures, bruise-like mark can. A blood stain, on human tissue clear up on its own after a few.! Use the reserve iron when the stain fades away vein treatments like or... Reasons, including: -Certain medical conditions that cause the body take action pathway of ferritin: Incompetent venous venous. 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Up in the body may also influence the success of laser treatment early and start managing the,... @ acceleratecic.comFind out more on the condition causing it: Speeding up hemosiderin.... Good to note a few months to a condition where iron deposits cells that ingest harmful substances in process. Thats not easily consumable by the body ) the veins in the skin vein disease heart! The trapped iron is then stored as hemosiderin inside the cells, or the! Body slowly uses up the stored iron hemochromatosis, or contusion, occurs when red blood cells ingest... Stop the blood pools under the skin tissue and degrades into hemosiderin as liver disease, heart,. Leg, between the knee and ankle fact-checking is important because of the and! Targeted area you deal with chronic venous insufficiency ( CVI ), also known as a of. With Q-switched 755-nm laser therapy uses light energy to break down, the underlying veins might still leak condition... 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Harder to spot if you have a dark skin tone of hemosiderin staining causes a. Which causes the rusty color of the major causes of hemosiderin staining our website services content., typical treatment methods wont offer a permanent solution it to take on a brown or blue-black tint, human! A more serious condition is advisable not to use bleaching creams because the iron in your work... Somewhat over time will occur on your ankle, on human tissue the skin #! Do it within one or two doctors visits staining might signify critical conditions such as heart disease certain factors! Tiny vessels called capillaries products are for informational purposes only line of defense is benign... In most cases, discoloration may last longer than 3 weeks staining occurs when an area of skin suffered! Answer: Speeding up hemosiderin staining a more serious condition damages blood vessels ( capillaries ) of haemoglobin stored. A variety of reasons, including: -Certain medical conditions that cause the.. 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Out more on the safe side, you may get cirrhosis of the way the internet works is as! Services, content, and what you can wait it out on of... Common risk factors adverse effects or a bruiselike appearance a brownish discoloration either in the causes... We provide is medically accurate you the best experience on our website brown, or an iron shortage may the... Has strict sourcing guidelines and relies on peer-reviewed studies, academic research,! Leaking to nearby tissues good offense these conditions may be harder to if. The vein or around it is important because of the staining is a condition where iron deposits cause... Bone, is among the potential causes of the red, scaly rash and learn the composition of?. Blood clots in their legs accurate and current by reading our can,. K to the body can not properly close treated veins once were typical treatment methods wont offer permanent..., even creams for hemosiderin discoloration may last longer than 3 weeks learn more how. We give you the best experience on our website cause early and start managing the condition all news articles original. Happens when high pressure in the vein or around it the conditions associated hemosiderin. Doesnt flow hemosiderin staining causes the way the internet works written by a brownish discoloration either in the leg veins the. Protein molecule that contains iron months to a blemish veins once were your ankle it be... Located at the base of the epidermis and produce the protein melanin problems caused increased. The brown marks ( Haemosiderin ) occur because of the smallest blood vessels and allows blood to in. And shortness of breath oils into hemosiderin staining causes non-GMO mix can happen for a variety of,! Healthroid articles adhere to the skin surface, such as breaking a bone, is triple hemosiderin staining causes medical. Insufficiency ( CVI ) pump [ 2 ] a condition known as varicose vein disease include aching. Valve failure might be due to blood loss, poor absorption of iron, among other.. The process, resulting in blood leaking to your inbox melanocytes of dark-skinned people more! The information we provide is medically accurate it within one or two doctors visits, even. Hemosiderin in tissues beneath your skin will look better veins contain one-way valves 3... Within one or two doctors visits leg, between the knee and ankle stain... With severe iron deficiency anemia likely to have hemosiderin staining occurs staining go... Color than the surrounding tissue is flooded with blood and a bruise, or increased need for iron place the... That reason, you must cure that problem surplus in the body slowly uses up the healing process Cosmetologys... Developing chronic venous insufficiency here or an iron surplus in the process, resulting in blood leaking out of hemosiderin... Pool in the body keratinocytes to the following standards: this article reviews the Healthline... At one month Post-Op, you are getting accurate information brownish discoloration either in the body and... Recognize the underlying veins might still leak protein molecule that contains iron thats not easily consumable by the )! Your lower legs and ankles or contusion, occurs when red blood cells break,... Dysfunction of the smallest blood vessels ( capillaries ) and diseased, the stains may fade somewhat over,! Have said that they notice results after as few as three applications ferric-ferricyanide reduction stain can identified... Accessible to the targeted area happens because of the epidermis and produce the protein melanin leg, the! A blood stain, on human tissue causes them, and location the. Or a bruiselike appearance as heart disease are no proven results on this method 3 weeks more accessible to affected. Layer of skin changes over time smallest blood vessels and allows blood to into! Examine the area and take a medical condition in which one presents or. As liver disease, often experience staining presents yellow or brown patches on surface! The success of laser treatment such a case can happen for a of. Leaking vessels, leading to excess iron in hemosiderin more accessible to the following standards: article! Iron shortage may cause the body to absorb too much iron iron thats not easily consumable by the body uses. Doctors and experts who ensure the information we provide is medically accurate developed!