Can you drink alcohol while taking milk thistle? Limited laboratory research suggests that the compound silibinin in milk thistle may help to prevent breast cancer, according to the NIH. There are 4 drugs known to interact with The Food and Drug Administration (FDA) has not approved milk thistle for the treatment of cancer. In: StatPearls. Medical News Today only shows you brands and products that we stand behind. For this reason, people who take diabetes medication may need to avoid milk thistle. Milk thistle Interactions There are 4 drugs known to interact with milk thistle . You can learn more about how we ensure our content is accurate and current by reading our. Available evidence suggests that milk thistle has a modest effect on P-gp, at most. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. Check with your physician if you have any of the. Milk thistle may cause an allergic reaction in those with allergies to plants in the same family, like ragweed, chrysanthemum, marigold, and daisy. Cathy Wong is a nutritionist and wellness expert. 2018;9:1903. doi:10.3389/fimmu.2018.01903. Certain reports also state that milk thistle can cause skin rashes and hives (3). The active ingredient in milk thistle may help to reduce inflammation. Results from clinical trials of milk thistle for liver diseases have been conflicting or havent been clinically meaningful. Studies show that silymarin may help ease inflammation and promote cell repair. List Milk Thistle Capsule side effects by likelihood and severity. We know little about whether milk thistle is effective in people, as only a few well-designed clinical studies have been conducted. Milk thistle is available as a supplement from many health food stores. A very serious allergic reaction to this product is rare. Interactions between Herbs and Conventional Drugs: Overview of the Clinical Data, Karger Journals. Evidence and risks, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, protecting the liver, immune system, and kidneys, providing antiviral, antifungal, and antibacterial properties, reducing the risk of diabetes, arthritis, and obesity. Check out the infographic below to learn more about the benefits of milk thistle.SaveIllustration: StyleCraze Design Team. Check if they have been certified organic following U.S. Department of Agriculture (USDA) regulations. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Call your doctor for medical advice about side effects. Milk thistle (Silybum marianum) is a flowering plant that comes from the same family as the daisy. Yes, you can drink alcohol while taking milk thistle. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. StatPearls Publishing; 2022. You may report side effects to FDA at 1-800-FDA-1088. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Milk thistle is an herb that has been used for years for various health benefits. Milk thistle is sold as an oral capsule, tablet and liquid extract. It can be consumed in supplement form or as a tea. Although some studies have shown positive results on milk thistle for people with chronic hepatitis C virus (HCV) infection, the overall research does not show a benefit. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Milk thistle can also cause an allergic reaction in some people. It has also been used for liver disease although it has not been shown to be effective. 2014;2014:941085. doi:10.1155/2014/941085. Mothers who used milk thistle to boost their milk production reported unwanted weight gain along with irritability and nausea (16). milk thistle. Deng JW, Shon JH, Shin HJ, et al. Rambaldi, A.; Jacobs, B.; Iaquinto G, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. Consult your doctor before using this product. Thank you, {{form.email}}, for signing up. No supplement is intended to treat, cure, or prevent disease. Silymarin, a Promising Pharmacological Agent for Treatment of Diseases, Iranian University of Medical Sciences, US National Library of Medicine, National Institutes of Health. Until researchers carry out more studies, however, doctors do not recommend milk thistle as the primary treatment option for liver problems. Cochrane Database Syst Rev. It is now found throughout the world. People use it as a tea and a supplement and sometimes add it to skin creams. Phytomedicine. It is not yet clear whether milk thistle is equally beneficial for bone loss with a different cause. Enter other medications to view a detailed report. Continue reading. Gufford BT, Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF. Milk thistle could play an essential role in supporting bone health. If drinking milk thistle tea, it is best to limit intake to 6 cups a day. More studies with human participants could allow scientists to say with certainty that milk thistle supports a persons immune system. The common name, milk thistle, is derived from the "milky white" veins on the leaves, which, when broken open, yield a milky sap. The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity. However, few of these claims are supported by solid evidence. 2014;97 Suppl 11:S31-S40. When possible, choose a supplement that has been tested by a trusted third party, such as USP, ConsumerLabs, or NSF. Consult your doctor for more information if you have either of these serious conditions.Some herbal/dietary supplement products have been found to contain possibly harmful impurities/additives. Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects: summary. Phytomedicine. Calm an upset stomach. Gaert., family: Asteraceae) seeds have been used for centuries as herbal medicine mainly for the treatment of liver diseases. J Med Assoc Thai. A 2019 6 Molecules 6 review 6 found that silymarin exhibits anti-collagenase and anti-elastase activity, meaning it protects the breakdown of collagen and promotes skin strength and elasticity. This suggests milk thistle may be beneficial for those looking to lose weight. Milk thistle may lower blood sugar levels in people with type 2 diabetes. Milk thistle may interfere with the following medications, because both milk thistle and these medications are broken down by the same liver enzymes: Allergy drugs -- such as fexofenadine (Allegra) Drugs for high cholesterol -- such as lovastatin (Mevacor, Altocor) Rambaldi A, Jacobs BP, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. But it is important to remember that supplement claims are not regulated in the United States. Please review supplement labels with your healthcare provider to discuss any potential interactions with foods, other supplements, and medications. MNT is the registered trade mark of Healthline Media. Its resources include publications (such as Dietary Supplements: What You Need To Know) and fact sheets on a variety of specific supplement ingredients and products (such as vitamin D and multivitamin/mineral supplements). Learn, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. According to researchers, these findings suggest that silymarin may improve diabetes symptoms like oxidative stress and inflammation. However, the evidence is conflicting. Researchers must carry out more studies on humans to confirm the effects of milk thistle on cognition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Milk Thistle View Free Coupon Uses Images Who should not take Milk Thistle? Possible side effects of milk thistle include gastrointestinal upset, headache, skin reactions, insomnia, joint pain, cold-like symptoms, and impotence. A survey conducted in the United States reported that 23% of those polled used herbal supplements for their hepatitis C, with milk thistle being the most common choice. It could also have similar effects on the body to estrogen. Milk thistle may produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy). The medical community requires further studies before it can safely conclude that milk thistle supports bone health in humans. Milk thistle has not been implicated in causing liver injury and is still used widely as a liver tonic in patients with acute and chronic liver diseases. Ebrahimpour, K.; Gargari, B.; Mobasseri, M. et al. Milk thistle is also available as a tea. Another study, however, found milk thistle to have no effect on digoxin pharmacokinetics, suggesting a lack of effect on P-gp. Eur Endocrinol. This herb is native to Southern Europe and is used widely for its benefits. Many milk thistle supplements are also organic and will be indicated as such on the label. Milk thistle has a range of potential health benefits due to its active ingredient, silymarin, which is an antioxidant. Although milk thistle may be helpful in hepatitis C, more research is needed to support these claims. content is best viewed in IE9 or above, Firefox and Google Chrome browser. Dupuis ML, Conti F, Maselli A, et al. Mulrow C, Lawrence V, Jacobs B, et al. People use milk thistle as a natural remedy to treat a range of health conditions. This publication is not copyrighted and is in the public domain. Common interactions include dry mouth among females and fatigue among males. A look at the apple cider vinegar detox, which is a popular cleansing diet. There is no standard dose of milk thistle, so it is best to read the dosage suggested on the packaging. Also known by its scientific name, Silybum marianum, milk thistle grows mostly in California, although it can be grown in many other warm climates as well. Content is best viewed in IE9 or above, Firefox and Google Chrome browser. The milk may have fallen on the leaves, leaving white marks. 2016;5147468. doi:10.1155/2016/5147468. Take this product by mouth as directed. National Center for Complementary and Integrative Health. Milk-thistle Amlodipine Milk thistle and Amlodipine drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported among people who take Milk thistle and Amlodipine. We comply with the HONcode standard for trustworthy health information. jaundice. 3. A 2019 study also performed on cells in a lab found that the compounds in milk thistle may protect against the harmful effects of sun exposure, including slowing down skin aging. Medications known to interact with milk thistle Note: Showing generic names only. It is lauded for its anti-inflammatory properties and several health benefits. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. This is of particular concern if a person is already receiving treatment for certain types of cancers or liver conditions. Vegetable Oil: Nutrition Facts And Differences. Before using this product, tell your doctor or pharmacist of all the products you use. Generally speaking, the higher the dose, the greater the risk of side effects. Who should not take Milk Thistle Capsule? NCCIH has provided this material for your information. Olive Oil Vs. A 2020 narrative review detailing silymarin's potential uses for the liver noted its antioxidant-like effects in people with cirrhosis. Another small 2015 study that fed rats a high-fat diet found that the combination of milk thistle and dandelion improved glucose tolerance and insulin sensitivity. Some people claim it can help to treat: cirrhosis. Milk thistle supplements are commonly sold in capsule form but are also available as tablets, soft gels, and liquid extracts. Its seed might protect liver cells from toxic chemicals and drugs. Drs. Potensi Tinggi Setiap kapsul mengandung 1.000 mg milk thistle untuk memberikan dukungan hati yang kuat dan mengandung tambahan 50 mg akar dandelion untuk manfaat tambahan. Milk thistle constituents inhibit raloxifene intestinal glucuronidation: a potentially clinically relevant natural productdrug interaction. Soleimani V, Delghandi PS, Moallem SA, Karimi G. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. Milk thistle is a plant whose fruit and seeds have been used for more than 2,000 years as a treatment for liver and bile duct disorders. [Database subscription]. (2021). Rev Diabet Stud. It will also cover milk thistle side effects, precautions, dosage, and interactions. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. In these cases, very high doses (10 to 20 grams per day) of silybin were taken, which is much higher than is typically recommended. To establish that the product manufacturers addressed safety and efficacy standards, we: We do the research so you can find trusted products for your health and wellness. This product may contain inactive ingredients, which can cause allergic reactions or other problems. The mention of any product, service, or therapy is not an endorsement by NCCIH. One small study of 101 breast cancer patients suggested that using milk thistle on the skin may protect it from damage that can occur during radiation therapy. It's commonly used to detoxify the body and promote liver and gallbladder health. Spiny stems branch at the top and reach heights of 5 to 10 feet. This is not a complete list of side effects and others may occur. The name milk thistle is associated with the legend of Mother Mary. Consult with your healthcare provider if you experience these and other side effects to find out the best way to proceed. Herbal remedies are usually the talk of the town. How this happens is yet to be studied. He has been in the digital media field for over eight years. Milk thistle is promoted as a dietary supplement for hepatitis, cirrhosis, jaundice, diabetes, indigestion, and other conditions. Some of the studies have been of poor quality, too. Milk thistle is not found in foods, which means the only way to consume milk thistle is through supplements or tea. Clinical practice shows that milk thistle has a good anti-liver injury effect and can be used to prevent anti-tuberculosis drug-induced liver injury. You may report side effects to Health Canada at 1-866-234-2345. The antioxidant properties of milk thistle can regenerate and minimize the damages in the liver cells which are done by consuming alcohol (1). Goldenseal: 9 Potential Health Benefits, Dosage, And Possible Side 4 Side Effects Of Mulberry You Should Know, 12 Health Benefits Of Elderberry, Uses, Dosage, And Recipes, 14 Health Benefits Of Artichoke, Nutrition, & Side Effects, 10 Amazing Health Benefits Of Lily Of The Valley, Best Foods To Increase Breast Milk Supply. A different cause medical professional should be consulted for diagnosis and treatment of any condition. 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